Soul Eater Episode 45

Synopsis
Set in the Shinigami technical school for weapon meisters, the series revolves around 3 groups of each a weapon meister and a human weapon. Trying to make the latter a "Death Scythe" and thus fit for use by the Shinigami, they must collect the souls of 99 evil humans and 1 witch.
Soul Eater is an anime that centers around meisters and their weapons and their mission to collect 99 evil souls and 1 witch soul. Upon doing that the meister's weapons will become a Deathscythe, which is the highest title for a weapon. Maka, Soul Eater, Black Star, Tsubaki, Death the Kid, and Patty and Liz Thompson are the characters Soul Eater revolves around. Besides taking the time to gather souls these students of Shibusen defend Death City from some of the most powerful of creatures while still attending school and trying to become stronger.

Episode 45 - "Demonslayer's Wavelength: Fierce Attack, Hatred of the Demon Hunter?"

Maka, Soul, Marie, and Crona continue their battle with Medusa and Stein, but are being overwhelmed. Marie asks Maka and Crona to concentrate on Stein, which gives her the chance to use the Wavelength of Redemption. Medusa uses the lull in combat to target Maka with an attack. Crona pushes Maka out of way and takes the full force of Medusa's attack. Crona is greatly injured by Medusa's vector blade. Maka is consumed by the madness and attacks Medusa with full force, and disarms her; before Maka can land a fatal blow, Stein protects Medusa, and this finally provides the opening Marie needs. Using the redemption wavelength, Marie saves Stein. Maka uses her demon hunter wavelength to defeat Medusa and save Rachel. Black Star finally reaches Baba Yaga's castle to battle Mifune.